美国北卡罗利娜大学（UNC） Chapel Hill校园传染病教授Ralph Baric的群组2015年 12月在自然医药学杂志（Nature Medicine ）发表了一篇根据由原来带源体马蹄蝙蝠的病毒SHC014结合沙氏病毒（SARS ）覆制而成的一种新型人工合成冠状病毒。此一人工合成病毒易于结合人体细胞并引起人类呼吸管道的致命感染，但不会让感染的老鼠致命，于原来之带原者蝙蝠则无影响。
为此，法国巴黎巴斯特研究所（ The Pasteur Institute in Paris）病毒学家Simon Wain-Hobson 曾批评此类人工合成病毒之举的不当，他认为：“如果此类新型病毒自实验室逸出，无人能够预测其结果（ If the new virus escaped, nobody could predict the trajectory,”）”
Ralph Baric 群组的原来的论文发表于2015 年12月之Nature Medicine 杂志，名为：
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
“ ….So, in my talk I talked about a longitudinal study that had been done by Zhengli Shi’s group at the Wuhan Institute on Chinese horseshoe bats, which led to a big shift in our thinking about these bat CoVs because it revealed they are much closer to the epidemic SARS strains than previously thought. Normally, we don’t evaluate anything beyond being reactive to the next emergent strain, but building on this study using our infectious clone system we had the opportunity to ask more questions – and that’s how this project started……”
估计他们合成使用的中国马蹄蝙蝠病毒是由葛行义和石正丽取得的，沙氏病毒（ SARS）的提供和和合成则是在 Menachery VD - Ralph Baric的美国UNC的实验室里出炉的。
----- Original Message ------
Received: Sat, 02 May 2020 12:06:28 AM CDT
From: "leeliang" <leeliang@usa.net>
To:
Subject: US investigating University of Texas links to Chinese lab Fwd: 介绍一种由中美研究人士合作而人工合成的致命新冠状病毒
My 04-09-2020 mail has identified a key paper that may shed some light on an intertwined relationship among UNC-UTG-Wuhan-Lab, and now the US government starts to investigate their relationships,
Some quotes from my 04-09-2020 email:
" Ralph Baric群组的原来的论文发表于2015 年12月之 Nature Medicine 杂志，名为：
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
其作者群为： Menachery VD, Yount BL Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS.
名单之中 , Ge XY 是湖南大学生物学院教授、博士生导师的葛行义，而 Shi Z 名单之中 , Ge XY 是湖南大学生物学院教授、博士生导师的葛行义，而 Shi ZL 就是中科院武汉病毒所教授的石正丽。除此之外，其馀人士大都是跟UNC 有关的研究人员；领衔的Menachery VD（Vineet D. Menachery ）是现任的德州大学(UT at Galveston) 分子生物学的助理教授，2017年之前他是 UNC (U of North Carolina at Chapel Hill)由Baric RS 所领导实验室下的的博士后，算算时间和按照论文作者排列次序的惯例，这个人工病毒的合成过程做的苦工可能就是他干的，殿后的Baric RS就是颇有名气的Ralph Baric，UNC的流行病学和分子生物学的大牌教授。。。
估计他们合成使用的中国马蹄蝙蝠病毒是由葛行义和石正丽取得的，沙氏病毒（ SARS）的提供和和合成则是在 Menachery VD - Ralph Baric的美国UNC 的实验室里出炉的。。。。"
I guess this investigation should be able to pinpoint where the virus was engineered if a fair investigation could be carried out. Should it be proven that the virus was indeed engineered within the United States then China's Wuhan could be ruled out, a good vindication.
